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Answer:

Slide A

4. Reactive endocervical cells

  • An inflammatory background
  • Actinomyces present
  • Cells occur in sheets and strips with some cell crowding
  • Nuclei are overlapping, slightly enlarged, variation in size and shape     

Slide B

5. ASC-H

  • Single oval cell with high N/C ratio

Figures 1: Reactive endocervical cells with vacuoles in slide A
 
Figure 2: Reactive endocervical cells with vacuoles in slide B

 

Conclusion

  • Slide A was signed out as ASCUS
  • It was reviewed by retrospective screening
  • Reactive and atypical metaplastic and endocervical cells are noted
  • The reactive changes can be explained by the effect of IUCD
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  • Slides B was signed as ASCUS
  • On review, the retrospective screening result was ASCUS not ASC-H
  • Reactive / atypical metaplastic and vacuolated glandular cells are noted
  • The cellular change is compatible with the effect of IUCD

Summary of IUCD effect

  • Atypical / reactive cells are seen: hypervacuolated endocervical cells, vacuolated metaplastic cells and endometrial cells
  • Actinomyces present
  • Inflammatory background without tumour diathesis
  • Single cells with high N/C ratio

Remarks

  • Abnormalities may coexist with IUCD effect
  • Recommend to remove the device for further assessment
6.

Last Update:Dec/04